Andy has played club rugby for Leicester Tigers, in the Aviva Premiership, and a season loan at Leeds Tykes, now Yorkshire Carnegie, in National Division One. He made his Leicester debut at Welford Road against Gloucester as a replacement.
Following a loan period at Leeds, Andy ended his contract with Leicester Tigers to join Yorkshire Carnegie full-time. On 19 August 2008 Tuilagi was confirmed as the last signing that would be joining Guinness Premiership side Sale Sharks on a four-year contract.
In November 2011 Andy joined Newport Gwent Dragons. He made his debut against Glasgow Warriors on 4 December 2011. He left Newport Gwent Dragons at the end of the 2012-13 season.
Andy returned to England in 2014 as signed for Newcastle Falcons in the Aviva Premiership on a two-year contract from the 2014-15 season, where he will join with his brother, Alesana Tuilagi.
Andy became the youngest player to play for Samoa at aged 19 years and 27 days when he made his debut in July 2005 against Tonga, where he scored a try to also become the youngest player ever to score for Samoa.
He was named in the 2007 Rugby World Cup squad, but was forced out of the tournament through injury. Since then he has been dropped out of favor in international rugby, his last call up coming in 2014 after 5 years out of the side.
CAREER IN NUMBERS
2005–2006 Leicester Tigers
2006–2008 Yorkshire Carnegie
2008-2011 Sale Sharks
2011-2013 Newport Gwent Dragons
2014-2016 Newcastle Falcons
2016-2017 Tarbes Pyrénées Rugby
Andy played 118 professional games for club and country and scored 80 points.